News

Discover the BioFIT 2015 preview program 

 

All about BioFIT – from all the details of the Conferences Program, the Presenting Technologies sessions and the Hosted Events to the Full Agenda and lot more :

http://www.biofit-event.com/strasbourg/wp-content/uploads/2015/09/BioFIT2015-ProgramPreview.pdf

 

Institut Charles Sadron/CEA :new optimized molecular architectures

Molecular adherence governed by autoadjustable polymeric chains
Bio-adhesive phenomena control the proliferation and displacement of multicellular organisms, but they also play an important tole in the development of intelligent medication carriers, for example by allowing them to recognizing tissues to treat. 
The Charles Sadron institute (CNRS), in collaboration with a team from the interdisciplinary laboratory of nanometric and supramolecular organization (CEA) has developed new optimized molecular architectures to better control their bio-adhesion. 

These discoveries have been published in “Nature Communications” magazine. 

 

More information: CNRS - laboratoires de l'institut de Chimie

 

 

LIT :A new path to treat Crohn’s disease

Teams from the Laboratory of therapeutic innovation (LIT, CNRS/Unistra) and Baylor University Medical Center (Dallas/USA) have synthetized a natural product derivative that exhibits powerful anti-inflammatory effects in a variant of Crohn’s disease developed in mice. 
That work opens promising perspectives to improve currently inefficient tratments for this disease. 

Results have been published in “Inflammatory Bowel Diseases” magazine.

 

Source CNRS Alsace : http://www.alsace.cnrs.fr/webdel/actus.del

 

 

IGBMC :Muscle « built » from stemcells

 

A method for obtaining muscle fibers and satellite stemcells from embryonic stem cells and iPS has been published in Nature Biotechnology on September 8, 2015.
It is a major biotechnology breakthrough by the team of Olivier Pourquié from the Institute of Genetics and Molecular and Cellular Biology (IGBMC/Inserm-Université de Strasbourg-CNRS) and Harvard University (United States), with the support of AFM-Téléthon.

 

 

Source INSERM Grand Est: http://www.grand-est.inserm.fr/actualites/du-muscle-fabrique-a-partir-de-cellules-souches

 

 

 

A powerful method for studying the structure and function of RNA

The identification of functionally important residue and structural patterns in RNA is a long and complex process.

Researchers from the molecular and cellular biology Institute (IBMC, CNRS) from the Roland Marquet team, associated with german, australian, and chinese researchers, have developed a powerful method for reaching that goal, using functional separation of a library of random mutants and their analysis by high throughput sequencing. 

 

This study is published in the Nature Methods journal.

 

Source : site CNRS 

 

 

Imitating viruses for delivering medicine at the heart of cells

Viruses have the ability to distort cells normal functions to infect them. Drawing on their modus operandi, researchers from the bioactive molecules conception and application laboratory (CAMB, CNRS/Unistra), in particular Guy Zuber, have developed a « chemical virus » able to cross the double lipid coat that delineates cells before breaking down in the intracell environment in order to deliver active molecules. 

To achieve this, the researches used two polymers they designed and that have auto-assembly or dissociation capabilities based on environmental stimuli. 

 

That research is the result of a collaboration between chemists, biologists, and biophysicians and is published in the September 1st issue of the Angewandte Chemie International Edition journal.

 

Source : CNRS Alsace

 

 

Peptidic auto-assemblies controlled by smart surface

A Charles Sadron Institute team (ICS, CNRS), made up in particular from  Pierre Schaaf, Fouzia Boulmedais and Loïc Jierry, collaborating with researchers from the biomaterials and bioengineering unit, has recently demonstrated how the surface of a material can induce a localized auto-assembly process and can thus control the resulting tridimensional supramolecular architecture.

This research has been published in the Angewandte Chemie International Edition journal.

 

Source : CNRS Alsace

 

 

Discover the press release about BioFIT 

 

December 1st & 2nd, 2015: Strasbourg is hosting BioFIT, one of the leading European business conventions in Life Sciences

 

 

BioFIT is the central platform in Europe for Open Innovation, technology transfer and collaborative research in Healthcare and Life Sciences and has now become an indispensable instrument for exchanges and partnerships between stakeholders in industry and public-sector research.

 

After the first three BioFIT editions in Lille, in 2015, the event is to be held for the first time in Strasbourg, a city in the middle of the Franco-German-Swiss BioValley and a center of excellence for therapeutic innovation.

 

This major international event is co-organized by Eurasanté, the Lille economic development agency, the Lille Nutrition Health Longevity cluster, Conectus Alsace and the Alsace BioValley cluster.

 

Read more of the press release HERE