Icube Seminar in june

ICube-MSII seminar
Biophotonics and The Future of Personal Health Care


Date: 13/06/2016 at 2.00pm Venue: Telecom Physique Strasbourg (A207)


Biophotonics technologies can be designed to provide quantitative, dynamic information about tissue structure and biochemical composition. Their impact spans from medical diagnostic and therapeutic devices to consumer-based wearable sensors. With advances in device miniaturization and high performance photonics components, the line between conventional medical instruments and consumer devices is becoming increasingly blurred. Health care economic pressures are further accelerating this ambiguity by shifting clinical attention from expensive disease treatments to strategies for cost-effective disease management and prevention.This talk introduces emerging Biophotonics technologies that are capable of characterizing tissue structure and biochemical composition spanning from micro-to macroscopic regimes. We will illustrate the power of both wearable and non-contact optical devices for assessing tissue functional parameters including: tissue blood, water and lipid content; tissue oxygenation and oxygen consumption, heart and respiration rate, and tissue blood flow. Finally, we will consider projected trends in development that are expected to impact how we generate, access, and manage this complex information and improve outcomes for individual patients.


Biosketch Bruce J. Tromberg, Ph.D.
Laser Microbeam and Medical Program,
Beckman Laser Institute and Medical Clinic,
University of California, Irvine 92617-1475
Dr. TROMBERG is the Director of the Beckman Laser Institute and Medical Clinic (BLI) at the University of California, Irvine (UCI) and principal investigator of the Laser Microbeam and Medical Program (LAMMP), an NIH National Biomedical Technology Research Center. He is a Professor in the departments of Biomedical Engineering and Surgery, co-leads the Onco-imaging and Biotechnology Program in UCI’s Chao Family Comprehensive Cancer Center, and has been a member of the BLI faculty since 1990. His research interests are in the development of quantitative, broadband Biophotonics technologies for characterizing and imaging tissue structure, function and composition across spatial scales.




ICube seminar "Filling without drilling" Advances of Lasers in Dental Applications


Date: 16/06/2016 at 10.00am Venue: Telecom Physique Strasbourg (A302)

During the last few decades, laser technology has continuously developed, to the point where new types of lasers such as ultra-short pulsed lasers in the subpico second regime have entered medical and dental applications. In the early days, various laser trials with CO2 lasers to make teeth material more resistant to bacteria that cause caries were reported. The trials failed because thermal side effects damaged the enamel. Nowadays, the idea has experienced a renaissance with new lasers and a more adequate pulse regime. In the late 1980's, the first experimental work demonstrated that Er:YAG lasers can be used to ablate dental tissue such as enamel and dentin. While the first system used an articulated arm for the light transmission, the next generations were equipped with fibre technology which make the application much more flexible. Starting with caries removal and cavity preparations, more application modalities by simply changing the handpiece has made the laser a universal tool in dentistry. Root channel disinfection, soft tissue corrections by ablation and periodontal applications with removal of infected plaques are new avenues of investigation. Treatment of periimplantitis is the latest application in which there is no mechanical alternative. The laser pulses remove the infected bone around the implant and sterilize the surface of the structured implant. Thus implants can be saved so that the growing bone is able to fix them again. Now, in the third generation of lasers, both detection and therapy can be combined with in the same handpiece. This is important in parodontology in which plaque has to be removed without visual contact by the dentist. Such new technology would also be possible for example in treating keyhole caries which develop with in the dentin under the enamel. In this case, it would be possible to pass a fibre through a small hole in order to save sound enamel, to scan over an angle so as to detect where infected material is to be ablated and to then remove the caries in the same procedure. This is not far from becoming a reality, especially with the development of new filling materials adapted to this procedure. In addition, laser sources are becoming smaller and more powerful and diode pumped fibre lasers are replacing solid-state lasers. The broadening of the wavelength spectrum of laser sources also facilitates the selective photothermolysis. Laser tissue diagnosis will become even more important than laser therapy procedures. Combining both online diagnosis and therapy will be a large step forward and breakthrough for safe and effective laser treatment. Tissue thermal damage can be avoided, which means less pain for the patient during treatment and is also likely to reduce the fear that many people have of the dentist. Lasers will eliminate the noise of the dental instruments that to some patients is nearly as disturbing as the physical discomfort. This demonstrates that laser technology has still enough potential for new developments.


Dr. Todor Petrov is a research fellow at the Laboratory of Metal Vapor Lasers (LMVL), ISSP, Bulgarian Academy of Sciences since August 1994. His PhD (April 1994) was on "Frequency Conversion of Copper Bromide Vapor Laser Radiation". He held a Volkswagen-Stiftung postdoctoral position at the AEEO, Ruhr Universität Bochum, Germany (1997) on “UV lasing in capacitively coupled Radio-Frequency excited He (Ne) Copper vapor discharge”. Each year between 2002-13 he was Guest Professor at the Institute for Laser Science, University of Electro-Communications, and Tokyo, Japan. His work was related to the study of nonlinear optical phenomena generated by fs laser pulses in glassy matrices as well as in thin metal films. He has worked for eight national research projects (2 as project leader) and four international projects (1 as project leader). Currently, he is an associate professor at the LMVL, ISSP. His main fields of scientific research include the development of new laser systems, nonlinear optical phenomena, laser–matter interaction, ultrafast laser processing, laser applications in dentistry and medicine.
FMTS seminar